Researchers at the US National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda have identified two previously unknown antibodies that can neutralize the omicron strain of coronavirus. Their article was published on the website medRxiv.
The study says that we are talking about antibodies called NE12 and NA8. They were isolated using a new technique developed by scientists led by Patricia Farci from NIAD. It allows you to quickly isolate and multiply antibodies to COVID-19 from the blood of patients and evaluate their effectiveness.
Based on this method, the researchers extracted DNA strands from the immune cells of 12 patients and placed their key regions in the bacteriophage genome. Subsequently, fragments of antibodies began to appear in its protein shell. Scientists have prepared several hundred of these viruses and tested their ability to combine with fragments of the SARS-CoV-2 shell. As a result, they found the NE12 and NA8 antibodies, which effectively neutralized the Omicron particles. According to scientists, they are also able to cope with the variants of the coronavirus “delta”, “alpha”; and “beta”.
Study participants conducted experiments on hamsters, which proved that the molecules they isolated were superior to all existing preparations based on monoclonal antibodies approved by the World Health Organization (WHO). Scientists believe that NE12 and NA8 will create new drugs for coronavirus. According to scientists, they will be able to protect patients from severe forms of the disease.
Earlier, the head of the Ministry of Health of the Russian Federation, Mikhail Murashko, said that the risk of re-infection with coronavirus with an omicron strain increases five times.